Just take on a conventional second job to make the money. If you reduce your living expenses at the same time, that will make your earning requirements for the second job lower.
Aside from inventing an innovative idea or finding an existing business idea that is good but not yet being done, that's the only sure way to make the kind of profit you're needing.
I'm sorry you're in such a position and can only hope that you are now cured of the medical ailments that got you into this position in the first place.
Sorry for downmodding you - I blame microscopic arrows and lack of undo.
Your advice is some of the best in this thread. Entrepreneurship is about taking on risk, which is exactly the opposite of predictable money.
Perhaps a second "conventional job" isn't what's called for, but consulting definitely is. The important part is to get paid now rather than hoping to strike it rich through sweat equity.
Aside from inventing an innovative idea or finding an existing business idea that is good but not yet being done, that's the only sure way to make the kind of profit you're needing.
I'm sorry you're in such a position and can only hope that you are now cured of the medical ailments that got you into this position in the first place.