Did you mean to write "America" instead of "the United States"? Because when the continent had only American Indians, there was no United States. And in fact for a long while after it was founded, they were excluded from citizenship.
Regardless, I'm sure we both agree that European conquest and colonization represented a giant change. It's false to imply that another such change isn't a change, by virtue of it happening once before already. Or to imply that therefore, the country is compelled to submit to such a change.